... demand for flavours and fragrances. He also cites and emerging market for chiral food addictives, including amino acids, fatty acids, vitamins and other natural products and their synthetic analogs which are generally more potent than the mixture of both chiral forms. Compound in medicine initially used as a sedative and an antiemetic until the discovery that it caused severe fetal malformations. Thalidomide was developed in the mid- 1950's and was found to induce drowsiness and sleep. The drug appeared to be unusually safe, with few side effects and little or no toxicity even at high doses. Further testing revealed that thalidomide was particularly well-sited to alleviating nausea and other symptoms associated with morning sickness in pregnant women. The drug's potentially harmful effects on the foetuses of certain mammals were not recognised during testing. 'Twenty million patients -almost 10 % of the US population- were exposed to five drugs withdrawn from ...

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