... can occur. * G2 phase: During this time the cell is producing proteins and continuing to increase in size. Even though DNA synthesis is confined to a narrow window, the synthesis of organelles occurs throughout interphase. Immediately before the next stage of mitosis the chromosomes will replicate so that each of them consists of 2 chromatids joined by the centriole. Stage 2 - Prophase Prophase is usually referred to as the 'true' stage of mitotic division, during which the cell undergoes several distinct changes: * The nucleoli disappear. * The chromatids shorten through the spiralisation and condensation of the DNA protein coat. * The mitotic spindle composed of microtubules and proteins, forms in the cytoplasm. Stage 3 - Metaphase * The nuclear envelope breaks up. * Polar fibers, which are microtubules that make up the spindle fibers, reach from each cell pole to the cell's equator. Stage 4 - Anaphase This stage is the most rapid, with the splitting of ...

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