... to the anterior pituitary gland. It is here that the GnRH controls the release of two protein hormones, luteinizing hormone (LH) and follicle-stimulating hormone (FSH) which are known collectively as gonadotrophins. Because the release of GnRH is in waves, consequently FSH and LH are secreted in waves too. These gonadotrophins are released into the general blood system and are transported to the gonads where they have their major effect. FSH lives up to its name and is the principal hormone for stimulating follicle growth in the ovaries. LH surges through the ovaries towards the end of maturation and just before ovulation, it causes the maturing follicle to 'rupture' and separate leaving the developing luteal cells behind. LH is responsible for the development of the CL and this in turn is responsible for producing progesterone. At the same time as the LH surge, the ovarian steroid hormone Oestradiol is released and ...

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