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... deacetylases, as well as homologous genes present in other organisms. This information was then used to suggest possible correlations between the function of the gene and its similarities to other homolog proteins; which will further be explained in this report. Methods: To carry out our investigation the methods used were web-sites databases that gave instructions. To start our first task was to search for the gene and uncover its background information. Then the database entry for HDAC 8 was used to collect the gene's general information, i.e. its proper name and gene family, chromosomal location, and reference mRNA sequence, the "BLAST" program on the NCBI's website was used to provide contrasting mRNA sequences for comparison against the HDAC 8 nucleotide sequence in FASTA format. The BLAST program was then used with the gene's protein sequence to identify other human HDAC proteins that showed significant similarities to HDAC 8. Sequential ...