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Words: | Submitted: Thu Jul 11 2002
... for DNA microarrays and has never been labelled as that. However the beginnings of cataloguing and annotating proteins started way before the human genome project was conceived. The first step was in a proposal for the Molecular Anatomy Program in Oak Ridge in 1960. This project intended on creating an inventory of cells at the molecular level as technology, either existing of envisioned would allow. This lead to the development of techniques such as fractionation of proteins, HPLC, and finally high-resolution 2D Electrophoresis in 1975. In 1980 in America there was an attempt to launch the Human Protein Index Project (HPIP) as a national objective but support was lost when the supporting senators were not elected. However in 1983 proponents of the HPIP suggested that a dual effort involving the complete sequencing of the human genome and a parallel protein project. Of these two, The Human Genome Project was the first ...
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