... that estrogen has substantial effects on the action of the Central nervous system (Maki et al 2001).? Previous studies have shown that estrogen may help protect neurons from oxidative stress and from the neurotoxity of beta-amyloid (Behl et al 1997)which are the plaques implicated in the pathogenesis of Alzheimer's Disease. Studies have also shown that estrogen modulates cerebral blood flow and glucose metabolism (Resnick et al 1998) ?. Resnick et al (1998)? examined regional cerebral blood flow in postmenopausal women during verbal and figural memory tasks to verify if estrogen determined the pattern of brain activation during memory task performance. They concluded that hormone replacement therapy (sstrogen suppliments) users and non-users have different patterns of cerebral blood flow to areas of the brain involved with memory, and different patterns of brain activation during performance of memory tasks (Resnick et al 1998).? Similarly Shaywitz et al (1999)? evaluated brain activation during verbal memory ...

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