... Once absorbed into the blood stream the drug is moved throughout the body and takes an active from, and is further biotransformed in the liver. The final stage of the pharmacokinetics is excretion, which takes place through the liver. Indications The use of ibuprofen as listed in Physicians' Desk Reference includeds temporary relief of headache, muscular aches, the minor pain of arthritis, toothache, backache, minor aches and pains associated with the common cold, the pain of menstrual cramps and the reduction of fever (pdrel). Directions A standard over the counter dose of Motrin IB is a 200mg tablet that should be taken every 4 to 6 hours. If needed the dose may increased to two, 200mg tablets but no more than six pills should be taken in a 24 hour period. This is the gold star standard for analgesic affects. However, if more effective anti-inflammatory affects are needed the dose can ...

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