... and it is used to determine the effectiveness of the drug, the dose, side effects and its metabolism.3 Phase I also provides information about the pharmacokinetics and pharmacological factors of the novel drug and from these studies, improvements are made for the phase II studies that are to follow.3 Choosing whether or not to take part in a clinical trial is one of the toughest decisions facing a person and most people don't really pay much attention to clinical trials until they are diagnosed with a serious illness such as cancer.2 Medical breakthroughs often make the news, but you don't usually hear about clinical trials themselves unless something has gone wrong i.e. the phase I TGN1412 trial that was carried out on anti-inflammatory drug at a research unit at Northwick Park Hospital. The drug was designed to treat conditions such as rheumatoid arthritis and leukaemia. Eight volunteers were involved in the ...

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